Question: What Medications Should Not Be Taken With Clopidogrel?

What antacids can be taken with clopidogrel?

– Patients who use clopidogrel and need a medication to reduce stomach acid can use antacids and most H2 blockers such as Zantac (ranitidine), Pepcid (famotidine), Axid (nizatidine), but not Tagamet and Tagamet HB (cimetidine)..

Can I drink coffee with clopidogrel?

Conclusions: Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Does clopidogrel cause stomach problems?

Easy bleeding/bruising, stomach upset/pain, diarrhea, and constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Although unlikely, serious bleeding in the stomach, gut, eyes, or brain may occur.

Can clopidogrel cause leg pain?

You may have muscle pain while you’re taking Plavix. It’s not known for sure why this occurs in people taking the drug. If you have severe muscle pain while you’re taking Plavix, call your doctor right away. They can check to see what’s causing your discomfort, and they’ll recommend whether you need medical treatment.

What should you not take with clopidogrel?

Do not take aspirin for pain relief (300mg tablets) or ibuprofen while you’re taking clopidogrel, unless a doctor has said it’s OK. They increase the chance of bleeding. You can take paracetamol together with clopidogrel.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.

How do you know if clopidogrel is working?

You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working. However, if bleeding is excessive, prolonged, or you notice blood in your urine or stool, seek urgent medical advice.

Which medicines should not be taken together?

5 Over-the-Counter Medicines You Should Never Take TogetherDangerous duo: Tylenol and multi-symptom cold medicines. … Dangerous duo: Any combo of ibuprofen, naproxen, and aspirin. … Dangerous duo: Antihistamines and motion-sickness medications. … Dangerous duo: Anti-diarrheal medicine and calcium supplements. … Dangerous duo: St.

What is the best time to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

When should you not take clopidogrel?

If you have certain health conditions such as a peptic ulcer or bleeding disorder you should not take clopidogrel, unless advised by a specialist. You should use clopidogrel with caution if you have liver or kidney problems. Clopidogrel must not be given to anyone under 16 years old, unless under specialist advice.

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

What foods are good to eat when you are on blood thinners?

HEALTHY CHOICES Some of the healthiest foods that you can eat, including foods like broccoli and spinach, are high in vitamin K. You might read or be told that you need to be aware of your vitamin K intake, because vitamin K can interfere with how warfarin works or make it less effective.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel. Acute-phase reactants were elevated.

Is it safe to take omeprazole with clopidogrel?

The FDA, MHRA and EMA discourage use of omeprazole and esomeprazole in patients taking clopidogrel. There is insufficient evidence regarding which PPI is least likely to interact.

What painkillers are safe to take with clopidogrel?

Painkillers. It’s fine to take paracetamol with clopidogrel. You can also take opioid-type painkillers such as codeine, co-codamol, tramadol or morphine alongside clopidogrel.

What drugs interact with clopidogrel?

Serious InteractionsSELECTED PLATELET AGGREGATION INHIBITORS/NSAIDS.CLOPIDOGREL/ESOMEPRAZOLE; OMEPRAZOLE; CIMETIDINE.CLOPIDOGREL/FLUCONAZOLE; KETOCONAZOLE; VORICONAZOLE.CLOPIDOGREL/ETRAVIRINE.CLOPIDOGREL/FELBAMATE.CLOPIDOGREL/TICLOPIDINE.CLOPIDOGREL/FLUOXETINE; FLUVOXAMINE.More items…